Melanin In Bloom: My Journal

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Melanin In Bloom: My Journal

Melanin In Bloom: My Journal

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Jablonski, Nina G.; Chaplin, George (11 May 2010). "Human skin pigmentation as an adaptation to UV radiation". Proceedings of the National Academy of Sciences. 107 (Supplement 2): 8962–8968. Bibcode: 2010PNAS..107.8962J. doi: 10.1073/pnas.0914628107. PMC 3024016. PMID 20445093.

Clark, J. M. The 3Rs in research: a contemporary approach to replacement, reduction and refinement. Br. J. Nutr. 120, S1–S7 (2018). We attempted to use the standard dye propidium iodide (PI) to validate that GFP-negative cells within nodules are dead. Surprisingly, PI staining did not stain nodule-encapsulated yeast cells, although there was staining in some of the hemocytes that surrounded the yeast cells, and the external periphery of the nodules (Fig. 1f). The absence of PI staining of the fungi is likely due to inability of the dye to penetrate the nodule fully.Castelvecchi, Davide (26 May 2007). "Dark Power: Pigment seems to put radiation to good use". Science News. 171 (21): 325. doi: 10.1002/scin.2007.5591712106. A Single Migration From Africa Populated the World, Studies Find". The New York Times. 22 September 2016. Mark Heiden (8 July 2020). "New biomaterial could shield against harmful radiation". Northwestern University . Retrieved 29 January 2023.

Pheomelanin [ edit ] Part of the structural formula of pheomelanin. "(COOH)" can be COOH or H, or (more rarely) other substituents. The arrows denote where the polymer continues. Larvae of the wax moth Galleria mellonella are commonly used as a model organism for studying fungal pathogenesis 3. G. mellonella larvae are readily available in large numbers at low cost. Their larger size (2–3 cm) relative to other model insects such as Drosophila melanogaster makes them amenable to experimental approaches requiring larger volumes of hemolymph, insect hemocytes, and soluble immune factors. The study of G. mellonella hemolymph can prove valuable for understanding insect immune responses to infection. G. mellonella are also commonly used as a model for studying mammalian pathogens, including human pathogenic fungi Cryptococcus neoformans and Candida albicans 19, 20, 21. While G. mellonella is a model for mammalian fungal infections because of similarities between the G. mellonella immune responses and the mammalian innate immune responses 3, a more thorough understanding of the insect immune response is needed to fully benefit from studying host-microbe interactions in G. mellonella. Brenner M, Hearing VJ (2008). "The protective role of melanin against UV damage in human skin". Photochemistry and Photobiology. 84 (3): 539–49. doi: 10.1111/j.1751-1097.2007.00226.x. PMC 2671032. PMID 18435612. Melanin protects Drosophila flies and mice against DNA damage from non-UV radiation. [37] Important studies in Drosophila models include Hopwood et al., 1985. [37] Much of our understanding of the radioprotective effects of melanin against gamma radiation come from the laboratories and research groups of Irma Mosse. [38] [39] [40] [41] [42] [43] [44] :1151 Mosse began in radiobiology in the Soviet era, was increasingly supported by government funding in the wake of the discovery of radiotrophic microbes in Chernobyl, and as of 2022 [update] continues under the Belarusian Institute of Genetics and Cytology. [43] Her most significant contribution is Mosse et al., 2000 on mice [38] [39] [40] [41] [42] [43] [44] :1151 but also includes Mosse et al., 1994, [42] Mosse et al., 1997, [42] Mosse et al., 1998, [41] Mosse et al., 2001, [42] Mosse et al., 2002, [41] [42] Mosse et al., 2006, [41] [42] Mosse et al., 2007 [42] and Mosse et al., 2008. [42] Plants [ edit ] Chemical structure of indole-5,6-quinone Yao, Zeng-Yu; Qi, Jian-Hua (22 April 2016). "Comparison of Antioxidant Activities of Melanin Fractions from Chestnut Shell". Molecules. 21 (4): 487. doi: 10.3390/molecules21040487. PMC 6273334. PMID 27110763.

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Chen, C. C. & Chen, C. S. Brugia bahangi: effects of melanization on the uptake of nutrients by microfilariae in vitro. Exp. Parasitol. 81, 72–78 (1995).



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