It’s up to you if you use your HA serum as part of your morning or your night-time routine; if applying in the morning, give the product time to sink in before applying moisturiser and makeup, as serum formulations can be quite runny and may cause your makeup to slide off if not properly absorbed. de, Maio M. The minimal approach: an innovation in facial cosmetic procedures. Aesthetic Plast.Surg. 2004;28(5):295-300. View abstract. Goa KL, Benfield P. Hyaluronic acid. A review of its pharmacology and use as a surgical aid in ophthalmology, and its therapeutic potential in joint disease and wound healing. Drugs 1994;47:536-66. View abstract. The serum promises softer, firmer skin, and we did experience those benefits. In fact, plumping was one of the biggest benefits we noticed. We saw a reduction in fine lines and wrinkles but an increase in fullness. After using this serum regularly, our skin looked healthier and more glowy. When I started taking PureHA I began to see improvements to my skin within two weeks”– DIANE, 60+ years

Ana Mansouri, MD, is a cosmetic doctor at Kat & Co Aesthetics based in the UK who specializes in injectables and aesthetics. This serum is an amazing choice for anyone dealing with hormonal changes such as pregnancy or postpartum. We saw a lot of improvements after using this serum for two months. At the start of the testing period, our editor had a couple of skin issues—namely some dry spots, rosacea-like redness along the cheeks, and uneven texture. Now that those concerns have practically vanished, this is our editor’s new go-to hyaluronic acid serum. Gold D, Nicolay L, Avian A, et al. Vaginal laser therapy versus hyaluronic acid suppositories for women with symptoms of urogenital atrophy after treatment for breast cancer: A randomized controlled trial. Maturitas 2023;167:1-7. View abstract. Liu YR, Liu B, Yang BP, Lan Y, Chi YG. Efficacy of hyaluronic acid on the prevention of intrauterine adhesion and the improvement of fertility: a meta-analysis of randomized trials. Complement Ther Clin Pract 2022;47:101575. View abstract.You should see smoother, less lined, more moisturised skin almost instantly and you will notice your skin feels softer, too," explains Paula, saying everything we want to hear. "Over time, fine lines and wrinkles will become less apparent, skin will maintain a youthful plump and supple feel, and be much less prone to showing signs of dryness and dehydration. Used as part of a skincare routine that includes daily sun protection, products with hyaluronic acid naturally restore the skin’s ability to look and act younger. It isn’t a miracle cure, but it’s a beautiful ingredient for maintaining your skin." Are there any downsides to using hyaluronic acid? Rolando M, Valente C. Establishing the tolerability and performance of tamarind seed polysaccharide (TSP) in treating dry eye syndrome: results of a clinical study. BMC Ophthalmol 2007;7:5. View abstract. Uthman, I., Raynauld, J. P., and Haraoui, B. Intra-articular therapy in osteoarthritis. Postgrad.Med J 2003;79(934):449-453. View abstract.

Even active ingredients that don’t always mix well with others, such as vitamin C and retinol, play nicely with hyaluronic acid. You can use them in the same routine, and hyaluronic acid can even counterbalance any sensitivity or dryness caused by certain active ingredients. The Mad Hippie serum contains quite a few antioxidants along with hyaluronic acid to combine brightening and hydrating benefits. At first the serum left our skin feeling a little tight, but after using it consistently our skin was smoother, brighter, and more hydrated. Our 5ml sachets contain a potent 17mg of pure fermentation-based mid-molecular weight hyaluronic acid, carefully complemented with 12mg (15% RDI) of vitamin C. This dynamic duo works harmoniously to replenish your body’s natural supply. As a naturally-occurring substance, hyaluronic acid is renowned for its safety and ease of integration into your daily life, becoming an ally in your quest for lasting beauty. SUITABLE FORChen WY, Abatangelo G. Functions of hyaluronan in wound repair. Wound Repair Regen 1999;7:79-89. View abstract. Duperre J, Grenier B, Lemire J, Mihalovits H, Sebag M, Lambert J. Effect of timolol vs. acetazolamide on sodium hyaluronate-induced rise in intraocular pressure after cataract surgery. Can J Ophthalmol 1994;29:182-6. View abstract. Origoni M, Cimmino C, Carminati G, et al. Postmenopausal vulvovaginal atrophy (VVA) is positively improved by topical hyaluronic acid application. A prospective, observational study. Eur Rev Med Pharmacol Sci. 2016;20(20):4190-4195. View abstract. Hashem AS, Issrani R, Elsayed TEE, Prabhu N. Topical hyaluronic acid in the management of oral lichen planus: A comparative study. J Investig Clin Dent 2019;10(2):e12385. View abstract.

So we all know hyaluronic acid to be the MVP of skincare—or, at least, that’s what you’ve read/heard/seen in every single article, commercial, and product description for the past year, right? (We get it, hyaluronic acid—YOU’RE POPULAR.) And although, yes, this little ingredient is usually the key to plump, glowing skin, it still needs to be used correctly or it could make your face sincerely unhappy. So if you have officially reached peak levels of confusion about WTF hyaluronic acid even is and how to use it, please allow myself and the experts to explain everything you need to know about hyaluronic acid for skin and the correct way to use it in your skincare routine. Meet the experts:The antioxidant trio of vitamin C, vitamin E, and ferulic acid make this serum suitable for those with oily, acne-prone skin. Our editor with oily skin had never used hyaluronic acid before, but noticed the difference after using this serum for eight weeks. New Product: Gelclair concentrated oral gel. Pharmacist's Letter/Prescriber's Letter 2002;18(7):180711.